The latest results from the SCALE Obesity and Prediabetes three-year extension trial showed that people who took Saxenda once-a-day for three years, in addition to making healthy changes to diet and exercise, were a whopping 79% less likely to be diagnosed with a new case of type 2 diabetes in that time frame compared to people who changed their diet and exercise alone (the placebo group)
Med 101 , e28628 (2022)
Adherence is the strongest predictor of success: This applies to any chronic medication, but it's particularly relevant for daily oral dosing
Now considered a landmark in the GLP-1 field, the article listed Mojsov as the first author and Habener as the last, a position customarily reserved for the senior author (Couzin-Frankel 8 Sept 2023
In separate randomized clinical studies, average weight loss reached up to 22.5% with Zepbound injection, 20.7% with Wegovy HD injection, 16.6% with oral Wegovy and 11.1% with oral Foundayo
Understanding GIP: The Second Incretin GIP received less attention initially than GLP-1 because early research suggested it might not be useful for diabetes treatment