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Zahra M, Shah M, Ali A, Rahim R

This review provides a new perspective for the accurate regulation of ferroptosis by modulating S-palmitoylation, thus may improve the overall prognosis through optimizing the treatment regimens or via enhancing the efficacy of existing therapies

It is reported that IGF-1 promotes hepatocyte proliferation, differentiation, cell cycle progression, and prolonging survival 30,31,32 , suggested that IGF-1 might repress cell premature aging and repair intrahepatic cells to ameliorate liver diseases

10.2147/DDDT.S358498 102 WangL.LiW.LiY.ChenG.ZhaoL.LiW.et al (2024)

Patent Term Extensions In the United States, the term of a patent covering an FDA-approved drug may, in certain cases, be eligible for a patent term extension under the Hatch-Waxman Act as compensation for the loss of patent term during the FDA regulatory review process

The Phase 2 data shows averages, and averages hide enormous individual variation