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While early open-label and phase 2 trials suggested potential benefits of arbaclofen in children with ASD, subsequent phase 3 randomized controlled trials failed to demonstrate significant efficacy over placebo on primary outcomes, despite favorable safety and tolerability profiles

Along with a lack of robust studies into these peptides, recent analysis of some of the products , externalsuggests that 8% may be contaminated with bacterial endotoxins

Sacco P, Decleva E, Tentor F, Menegazzi R, Borgogna M, Paoletti S, et al

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neuroprotective bile acids) [135]

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