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Abbas et al., 2023a) and exhaustion of antioxidant defenses, like downregulation of GSH and the Nrf2/heme oxygenase-1 signaling (Bu et al., 2018)

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Larger injection volumes (12mL) are more forgiving of small measurement errors than tiny volumes (0.30.5mL), where a 0.1mL miscalculation represents a 2033% dose variation

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