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B12 also contributes to nerve myelination (creating insulating fats around nerves) and breaks down homocysteine, a by-product of protein metabolism

Importantly, a salient PDS5B DNA binding mutation renders cells deficient in HR, DNA damage repair, and replication fork preservation upon replicative stress

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While B12 deficiency is rare, some individuals may suffer from chronic health issues or autoimmune conditions, which prevents the body from properly storing or absorbing vitamin B12

10.1016/j.brainres.2016.11.032 Brain Res

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