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The side effects of semaglutide, particularly the gastrointestinal ones, occur directly because of how the drug works

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HUBERMAN: That is to inject it or even take it orally, and that it will find the site of injury, right

Bunker and Bendelac 2018)

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The logic here is that the underlying pathology is not resolving as cleanly as an acute mechanical injury, and ongoing mucosal protection may require sustained peptide signaling