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It has been demonstrated that H 2 O 2 induces expansion of the endoplasmic reticulum in melanocytes, inhibiting tyrosinase (TYR) output, whereas quercetin markedly mitigates these effects ( 2 O 2 -treated melanocytes, and various combinations of quercetin, green tea extract, and folic acid synergistically prevented cellular damage

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however, isoflavones decreased serum PSA levels in Caucasian males and reduced IGF-1 and IGF-1:IGFBP-3 ratios in African American men, without impacting serum steroid hormones

Changes in antioxidant status of porcine ovarian granulose cells after quercetin and T-2 toxin treatment

Additionally, the adoption of standardized DOR models would facilitate more consistent and reproducible evaluations across studies