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A study in germ-free mice versus mice colonized with gut microbiota showed that the gut microbiota influences the hosts development of hypertensive organ damage, with TMAO and other microbial metabolites such as short-chain fatty acids (SCFAs) contributing to the phenotype (Avery et al., 2023)

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Pregnancy and breastfeeding - GLP-1 medications are not recommended during pregnancy or breastfeeding