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Assisted reproductive techniques are procedures used to increase the odds of fertilization by introducing sperm directly into the uterus (intrauterine insemination), exposing eggs to sperm in a fertilization medium in the laboratory (in vitro fertilization, IVF), or injecting a single sperm directly into an egg (intracytoplasmic sperm injection)

While studies in the meta-analysis described above excluded patients with a history of gallstones, clinical outcomes showed that higher doses and longer periods of use with GLP1-RAs have been associated with the greatest risk

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