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The regulation of NSC proliferation, self-renewal, and differentiation is finely regulated by changes in the surrounding microenvironment, or niche, in which NSCs reside (reviewed in Hepatocyte growth factor contributes to the maintenance of self-renewal and proliferation of NSCs in SVZ, which express MET and produce HGF
This conclusion emerges also from the several attempts made to use non-invasive stimulation of the cerebellum as therapy for focal dystonia
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Despite these shared traits, GS-S transferases coded for by the same genotype can have differing (though occasionally overlapping) substrate specificity and activity depending on the tissue they are found in and there is much research trying to discover what effect these genetic differences may have on an individuals idiosyncratic response to certain substances such as carcinogens
Katznelson, L
PLoS ONE 9 , e104397
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