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In challenge infections using WT UTI89 and UTI89 hlyA strains in nave, resolved and sensitized mice, we observed that hlyA infection, which does not activate caspase-1-mediated pyroptotic cell death, showed significantly increased bacterial burdens in sensitized mice compared with WT mice, whereas no differences were observed in nave and resolved mice (Fig

10.1074/jbc.M113.538157 318 ToflerG.MassaroJ.O'DonnellC.WilsonP

Its half-life of roughly 7 days enables convenient once-weekly dosing, which is why the standard protocol calls for a single injection per week rather than daily administration like some other peptides require

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Therefore, the uptake, release, storage and transport of iron ions in cells are all important factors affecting iron death

Relation of progesterone and DHEAS serum levels to 5-HT1A receptor binding potential in pre- and postmenopausal women