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Beyond classical antidepressants, mitochondria-targeted compounds, including antioxidants, metabolic modulators, and psychedelic-based interventions, further underscore mitochondria as a convergence point for diverse therapeutic mechanisms

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2014;9(5):e97554

On the 18th week of disease induction and on the last week of treatment, the mice underwent a 4 h fasting period (the food was removed, and the fructose water was replaced with normal water), after which fasting glycemia was measured, and blood from the tail vein was collected (~60 L) for insulin assessment