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Intratumoral administration of NBTXR- 3 has demonstrated safety and efficacy in enhancing radiotherapy outcomes for locally advanced sarcomas (Bonvalot et al

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4.4.3 Anti-inflammatory effects in acute central nervous system injury After acute injuries such as stroke and trauma, the activation of microglia and the infiltration of peripheral immune cells into ischemic tissues may trigger a robust and deleterious neuroinflammatory response (261)