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Description

To evaluate this combination, we used the Zero Interaction Potency (ZIP) model, which accounts for independent drug effects and is particularly suited for combinations of agents with differing targets, such as DPI and vincristine (38)

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Non-genotoxic p53 activation and blockade of Bcl-2 signaling synergistically induce apoptosis in AML through induction of Noxa and Bak/Bax heterodimerization

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