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Occur in 3045% of patients during dose escalation, and introducing a new supplement simultaneously makes it harder to identify which intervention is causing symptoms

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The FDA prescribing information lists diarrhea as an adverse reaction occurring in 30% of patients treated with the 2.4 mg injection compared with 16% on placebo in the weight-reduction trials

Weeks 58 More consistent appetite control Less mental focus on food Smaller portions feel satisfying Fewer sudden hunger spikes Weeks 812 Appetite feels regulated rather than restricted Eating patterns feel more natural Hunger is present but manageable Results feel steadier from week to week This is when appetite suppression often feels fully established

doi: 10.1016/S0140-6736(21)00536-5 17 MarsoSPBainSCConsoliAEliaschewitzFGJdarELeiterLAet al