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Clinical data from metabolic syndrome models show MOTS-c administration improves insulin sensitivity by 3040% and reduces visceral adiposity without caloric restriction

That is a very different statement from they do nothing. It means: The mechanistic rationale is real

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Science Behind B12 Shots and Weight Loss Most of the science regarding the shots has been related to their contribution to energy production and metabolism

Its likewise crucial to note that, as with any supplement, especially one that is relatively new and not extensively studied, caution must be exercised regarding its use