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Rein and Mueller 2017

Serum levels of IGF-1 and IGF-BP3 are associated with event-free survival in adult ewing sarcoma patients treated with chemotherapy

Osty J, Zhou Y, Chantoux F, Francon J, Blondeau JP

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Worsening of Tourette's syndrome has also been reported [see Adverse Reactions (6.2)]

On average, people regained about 0.4 kg per month, which is roughly 0.9 pounds per month, after stopping treatment