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Tirzepatide activates both GLP-1 and GIP receptors simultaneously, making it a dual agonist

Continuing treatment past month one is essential to see consistent fat reduction

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New Drugs 31, 13451354

In clinical studies, patients who discontinued treatment without achieving sustainable lifestyle changes often regained a significant portion of the lost weight

In adults with biopsy-confirmed metabolic dysfunction-associated steatohepatitis (MASH) and stage 2 or 3 fibrosis, semaglutide 2.4 mg achieved MASH resolution without fibrosis worsening in 62.9% of treated patients versus 34.3% on placebo at 72 weeks