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The temperature inside the chambers was regulated at 34.5 0.5 C to maintain the mouse rectal temperature at 36 0.5 C

In a study of Parkinsons disease that used a 6-hydroxydopamine-Parkinsons disease mouse model, treatment of SH-SY5Y cells with SFN was found to have a protective effect on the neurons, which was attributed to the observed increases in active nuclear Nrf2 protein, Nrf2 mRNA, and total glutathione levels and inhibition of neuronal tissue apoptosis [24]

FIGURE 25-2: Role of carnitine in the transport of long-chain fatty acids through the inner mitochondrial membrane

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