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Patients who have gone through dose titration often describe the first week after each increase as the time they notice digestive changes the most, with symptoms typically settling before the next scheduled step begins

Each named in research-context only (e.g., "studied in research models")

This rebound occurs because GLP-1 medications work by enhancing satiety signals, slowing stomach emptying, and improving blood sugar controleffects that fade when the drug leaves your system

The TNF/IL-23/IL-17 axis-Head-to-head trials comparing different biologics in psoriasis treatment

[13] The slow-transit constipation is due to decreased number of interstitial cells of Cajal (ICC) and alteration of myenteric plexus neurons which secretes substance P

Gastrointestinal issues: Its common for patients to experience stomach problems, including nausea, diarrhea, or constipation