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Early glucose-control improvements reflect the medication's action on GLP-1 receptors in the pancreas, which immediately enhance insulin secretion in response to meals

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For example, they examine cell migration, blood vessel growth, and healing models

At a $245 monthly price, the new model projected that Medicare would spend nearly $74 billion on GLP-1 drugs over 10 years if coverage expanded, with about $56 billion in downstream health savings thanks to better outcomes associated with diabetes, heart disease, and related complications