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Seek medical evaluation if symptoms are rapidly worsening, affecting balance or walking, involving weakness, or not improving after several weeks of supplementation

Long-term safety data particularly cardiovascular outcomes and effects on lean body mass will be critical for fully understanding retatrutide's place in therapy

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PMID:40005999

Over time, they can release inflammatory signals (often called the SASP, or senescence-associated secretory phenotype) that may contribute to tissue dysfunction seen with aging and some age-related conditions