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It requires careful dosing and endocrine follow-up to avoid ovarian hyperstimulation

GLP-1 (glucagon-like peptide-1) medications have recently grown in popularity, being often mentioned in weight management and diabetes discussions

Wegovy (semaglutide) is a once-weekly subcutaneous injection approved by the Food and Drug Administration for chronic weight management

Therefore, the androgen/estrogen ratio is modified in germ cells, and if testosterone is involved in the regulation of testicular functions, estrogens are also necessary not only in the control of gonadotropins secretion but also in the modulation of the Leydig cells development and steroidogenesis, as well as in the development and/or maintenance of spermatogenesis and spermiogenesis in some mammalian species (15)

5-HT7 receptor activation rescues impaired synaptic plasticity in an autistic-like rat model induced by prenatal VPA exposure