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Rial-Rodrguez, E., Kappe, C

3 Oxidative stress Oxidative stress is a disbalance caused by excessive production of prooxidant substances such as ROS and RNS and/or the antioxidant systems working inefficiently ( in vivo primarily by the mitochondrial respiratory chain during aerobic metabolism ( via a reaction between nitric oxide (NO) and superoxide, and nitrosoperoxycarbonate, generated via a reaction between peroxynitrite and carbon dioxide

Inflammation is a hallmark pathway of aging and is increasingly present in the brains of C57BL/6 mice [32]

Yoo HC, Yu YC, Sung Y, Han JM

10.1007/s00018-024-05532-5 168 XiaoleiW.YanbinG.NianxiuT.DaweiZ.YiminS.NanZ