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General healing support benefits overall tissue health

Considering that SOX9 plays important roles in chondrogenic mesenchymal condensation in embryonic limb formation [44] and in directly controlling the expression of various chondrogenic markers such as COL2A1 and ACAN [45, 46], hES-MSCs with high GSH levels also exhibited better chondrogenic differentiation potential

[6] Magnetic resonance imaging (MRI) scans of the brains of FMS patients have shown significant shrinkage in the hippocampus

Therefore, the presence of the VDR in these tissues indicates that calcitriol has functions in more cellular processes or that there are ligands other than calcitriol that can bind to and activate the VDR

This is a gap in the literature

Karimi, M., et al