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Over 80% of participants on the 12mg dose lost at least 15% of their body weight over 48 weeks

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Practical implementation considerations include: Post-meal activity : Even light walking (10-15 minutes) after meals may improve postprandial glucose levels Reducing sedentary time : Breaking up prolonged sitting with brief activity every 30 minutes Consistency over intensity : Regular moderate activity provides greater metabolic benefit than sporadic vigorous exercise Individualization : Exercise prescriptions should account for baseline fitness, comorbidities, and personal preferences to optimize adherence Special precautions are needed for those with diabetes complications, including proper footwear with neuropathy, avoiding high-impact or head-down exercises with retinopathy, and appropriate cardiovascular assessment before beginning vigorous exercise

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