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A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes

2014;35:S35S39

doi: 10.1016/j.ejphar.2015.11.004 40 GlatzJFLuikenJJ

Aspirin treatment reduced incident diabetes and slowed the increase in fasting plasma glucose over time among initially healthy older adults, the authors said in a statement

This effect is not interpreted as direct central satiety center action, but rather as a secondary response to sustained fat reduction, potentially involving improved leptin sensitivity in the setting of leptin resistance [24]