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The Pharmaceutical Benefits Advisory Committee will need to weigh the broad availability of incretin analogues for obesity management against the long-term health and economic costs of obesity to the Australian community

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While the strengths of our study include real-world applicability, validated outcome measures, and alignment with prior randomized evidence, certain limitations warrant acknowledgment

Incretin analogues also show beneficial effects in heart failure, peripheral vascular disease, renal disease, obstructive sleep apnoea and metabolic dysfunction-associated steatohepatitis and have potential neuroprotective properties