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Abstract This cohort study uses emulation target trial methods to evaluate whether semaglutide is associated with lower rates of opioid overdose among patients with type 2 diabetes (T2D) and opioid use disorder (OUD)

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Even when discounts are available, coverage is increasingly restricted by: Strict prior authorization requirements Step-therapy mandates Employer plan exclusions State Medicaid budget limitations Data also shows that many patients regain weight after stopping GLP-1 medications, reinforcing concerns that these drugs may function more as a long-term maintenance therapy rather than a finite treatment

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doi: 10.3389/fphys.2018.01672 11

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Thiebaud, N., Gribble, F., Reimann, F., Trapp, S

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