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These medicines show a clear doseresponse relationship

nephropathy, defined as a history of end-stage renal disease, renal dialysis, renal transplantation or death from chronic kidney disease

labels on their Depo-Provera injectable contraceptive despite having warnings on the medication in foreign countries

It has also been shown to lower the risk of strokes or death for both those suffering from type 2 diabetes and cardiovascular disease

There has also been impact on decreasing the chance of developing or recurrent cardiovascular disease such as heart attacks or stroke.

Desai MH, Mlcak R, Richardson J, Nichols R, Herndon DN