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In a cross-sectional study, mitochondrial fragmentation was specifically observed in the proximal tubules of kidneys from DKD patients

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Yes, daily use is considered safe within recommended dosages

Oxidative stress induced by mitochondrial and non-mitochondrial ROS and inflammation has been reported as the mechanism underlying insulin resistance ( Excessive ROS production is known to suppress antioxidant defense systems and physical exercise training has been shown to upregulate antioxidant defense mechanisms in several tissues and metabolic disorders (Sekhar et al., 2011