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Cellular GSH is found mostly in the cytosol, with the remainder spread across organelles (44)
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Future patent activity will likely need to shift toward formulation engineering, targeted delivery to reproductive tissues, and the development of semi-synthetic derivatives aimed at overcoming luteolins pharmacokinetic limitations
However, very high doses (10,000 mg/day) can cause minor side effects like an upset stomach, diarrhea, or bright yellow urine
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Doing so enables stabilization of the peptide
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