Future research should examine the potential role of GLP-1RAs in the treatment and prognosis of psychiatric and neurodevelopmental conditions
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The endoplasmic reticulum (ER) plays an important role in the folding and processing of newly secreted proteins and membrane proteins, the synthesis of lipids and sterols, and the storage of intracellular Ca 2+
This peptide, acts also as a hormone, and is expressed by both -cells and intestinal GLP-1 and GIP producing cells causing GLP-1 secretion in vivo via a yet unknown GPCR (162)
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Another study compared patients with obesity and hypothalamic damage, patients without obesity and hypothalamic damage, controls with obesity and normal-weight controls (Steele et al., 2015)