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Using the mass spectrometry (MS) assay, we found that the expression level of peroxisome proliferator-activated receptor coactivator 1 (PGC-1), the master regulator of mitochondrial biogenesis and function, was significantly altered both when CRAT was overexpressed in HEY cells and knocked-down in A2780 cells (Fig

What matters is not the scale, but how people experience connection, pleasure, and self-acceptance

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Coakley, G

Weight redistribution: Many women gain weight during menopause, particularly in the abdomen, which further increases insulin resistance

How GLP-1 Medications Support Your Weight Management Journey GLP-1 receptor agonists have reshaped treatment options for adults who struggle with body weight, especially during midlife when metabolism can slow and appetite cues shift