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Back, side, or groin pain: Pain in these areas can indicate that the infection has spread to the kidneys

For instance, IL-6, IL-8, and interferon-gamma (IFN-) concentrations have been shown to be elevated in horses 16 yr old, and older horses also had greater IL-6/IL-10 and TNF/IL-10 ratios

Feb 2023;53:224-237

[1] Tissue distribution of carnitine-biosynthetic enzymes in humans [edit] The tissue distribution of carnitine-biosynthetic enzymes in humans indicates TMLD to be active in the liver, heart, muscle, brain and highest in the kidneys

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