Effects of two-year vitamin B12 and folic acid supplementation on depressive symptoms and quality of life in older adults with elevated homocysteine concentrations: additional results from the B-PROOF study, an RCT
Waist circumference is a more informative marker of metabolic risk than body weight or BMI alone
It may provoke neuropathy symptoms at first
By inhibiting TGF- pathways and reducing collagen deposition, they protect podocytes and endothelial cells from injury, slowing CKD progression
Life Sci 272:119241 Hassanein EH, Shalkami A-GS, Khalaf MM, Mohamed WR, Hemeida RA (2019) The impact of Keap1/Nrf2, P38MAPK/NF-B and Bax/Bcl2/caspase-3 signaling pathways in the protective effects of berberine against methotrexate-induced nephrotoxicity
Its used to treat several skin diseases that are connected to inflammation including atopic dermatitis, rosacea or eczema