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Zepbound (tirzepatide) gained FDA approval for obesity treatment in 2024

Our extensive biochemical analyses of TGR combined with 3D structures of TGR complexes with various substrates, inhibitors, and in different redox states 17,30,31,32 , allow us to define in detail the catalytic mechanisms of TGR

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Regarding fat intake, the goal is not to promote the consumption of saturated fats but rather to emphasise high-quality unsaturated fat sources such as extra virgin olive oil, rice bran oil, wheat germ oil, and sunflower oil, which support both metabolic health and ketosis [106, 129]