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High-dose tirzepatide produces metabolic effects that semaglutide cannot fully replicate at any approved dose

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placebo 48.4% ( p = 0.0006) ( Tabalumab, a monoclonal antibody against BLyS that neutralizes membrane-bound and soluble BLyS, was assessed for its effectiveness in moderately active lupus in two large phase III clinical trials (ILLUMINATE-1 & 2)