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Overall, dietary histidine is critical not only for growth and metabolic functions but also as a protective agent against oxidative stress and hypoxic injuries in fish

References Nassar GN, Raudales F, Leslie SW

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Gedalia built TrufaMED around physician-led protocols, Joint Commission accreditation, and a standard of care usually reserved for hospital systems

This is made evident by the observation that hemozoin, the biproduct of erythrocyte digestion composed of heme molecules, is regurgitated by the worm, taken up by macrophages, and downregulates the Th2 types response seen during egg laying (170)