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Metformin Metformin is not FDA-approved for weight loss, but it produces modest weight reduction (2-3% of body weight) as a side effect of its primary mechanism, improving insulin sensitivity and reducing hepatic glucose production

[1] The effects were even more pronounced in aged animals

Garber A, Henry RR, Ratner R, Hale P, Chang CT, Bode B, et al

Jay Bacow: Let's hope they don't lose the first game and make him cry like you did a few years ago

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