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The mechanistic rationale is well established across preclinical and translational models, and a growing body of randomized trial and meta-analytic evidence supports the possibility of meaningful improvements in glycemic and inflammatory outcomes in appropriately selected patient groups

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Key Points: The Wegovy pill and Wegovy shot deliver the same FDA-approved active ingredient through different administration methods

This decision means that millions of Americans who rely on Medicare and Medicaid will not have access to coverage for weight loss drugs unless prescribed for other medical reasons