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Diabetes Care, 43(6), 1352-1355
Although up to six insulin-like growth factor binding proteins (IGFBPs) that bind to IGF-1 and IGF-2, but not insulin, have been identified (15), along with IGFBP proteases (16) we will not explore these in detail in this review
This suppresses antiviral immunity and promotes a liver microenvironment that enhances HBV persistence and hepatocarcinogenesis, accelerating both liver disease and tumor progression