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Mol Cell Biol

The main effects of Treatment (F( 1, 47 ) = 72.550, p 2 = 0.607, p = 0.000), Diet (F( 1, 47 ) = 6.798, p 2 = 0.126, p = 0.012) and sex (F( 1, 47 ) = 5.451, p 2 = 0.104, p = 0.024), were also significant, there were no other significant main or interaction effects ( p 0.062)

Clinical trials suggest that patients who achieve at least 5% body weight loss by months three to four are likely to be long-term responders

Retatrutide is not licensed by the MHRA or EMA and cannot be legally prescribed in the UK outside of regulated clinical trials

Authors contributions Writing and revising the manuscript (YH), assisting with the writing of the manuscript (CS, YC, YDL), supervising and revising the manuscript (JGF)

Insulin syringes require more manual control and attention but are completely adequate for safe injections