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4e, f, both G/D-CuP and D-CuP exhibited a significant reduction in the expression levels of pro-inflammatory cytokines

GCH1 plays an essential role in preventing ferroptosis by synthesizing the lipophilic antioxidant BH4, which helps reduce lipid peroxidation, and by remodeling lipid membranes to increase the reduced CoQ10 while decreasing the PUFA-PLs

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