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Subsequent research revealed that GHK has exceptionally high binding affinity for copper ions (Cu), forming a stable chelate complex (GHK-Cu) that is the biologically active form responsible for the peptide's remarkable effects

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for instance, lighter skin became apparent after administering high doses for treating other diseases

Traditional oral forms tend to have lower bioavailability because glutathione is broken down by enzymes in the digestive tract before reaching the bloodstream

However, collagen supplements are most effective when combined with a nutritious diet, sun protection, and a consistent skincare routine

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