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They were kept at constant environmental conditions throughout the experimental period with a room temperature ranging from 20 to 26C with regular light cycles of 12/1210/14 h light/dark, relative humidity at the level of rat cages of 4070% with room ventilation rates of about 1520 air changes/h

Federal spending is expected to increase under this demonstration due to paying for GLP-1s for obesity, which is not currently covered under Medicare, but the amount of the increase is unknown since CMS hasnt disclosed the projected cost

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FIGURE 2 3.3 Metabolic commonalities and differences between the two pneumonia models To compare metabolic features between the models, Venn analysis was conducted to compare the metabolic features between the two pneumonia models, revealing 17 shared differentially abundant metabolites with consistent directional changes in both models (Figures 3A, B)

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