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[35] If and when the disease progresses enough in a given case, the nephrologist or other practitioner and the patient will have to decide what form of renal replacement therapy will be used to treat end-stage kidney disease (kidney failure, typically stage 4 or 5 of chronic kidney disease)

you find it alongside co-factors that help it work

Damaging properties of singlet oxygen, 1 O 2 (both electrons paired, S = 0, multiplicity 2