Excitotoxicity activates cysteine aspartic proteases, which participate in NMDA-mediated apoptosis
GHK-Cu is a naturally occurring copper-binding peptide made of three amino acids: glycine, histidine, and lysine
In vivo experiments confirmed that the MPO/HOCl signaling pathway was significantly activated in the plasma and neurons of SOD1 G93A transgenic mice, which upregulated Caspase-3 expression, downregulated GPX4 and NQO1 expression, significantly elevated plasma MDA levels, promoted neuronal apoptosis, ferroptosis, and lipid peroxidation, and reduced motor performance in mice (Peng et al., 2022)
IV glutathione is not safe
Mediterranean diet and depression: a population-based cohort study
Some protocols split the daily dose into morning and evening injections