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Using topical vitamin C can result in less cell damage and better-looking skin. Free radicals can accelerate your skins aging, so on that front, vitamin C is already fighting the good fight

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Ice crystal formation physically damages the peptide structure, creating aggregation and reducing biological activity

Toxicol.2003,16(12), 1652-1660 40

However, the early onset of reduced craving suggests at least some direct central nervous system effects