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investigated the production of TMAO in the plasma and the urine by feeding patients an eight-ounce steak followed by a capsule of 250 mg heavy isotope-labelled L-carnitine [86]

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It helps minimize oxidative stress and neuronal damage by suppressing proinflammatory cytokines and stabilizing cell membranes 138,139

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and downregulates PI3K/Akt and mTOR pathway [125, 126], involved in regulating a variety of processes including insulin signaling, cell proliferation, and survival [127]

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